Defend RX

Defend Rx

Antimicrobial Masterbatches with BioCote® Technology

Defend Rx masterbatches from Compounding Solutions incorporate the silver ion antimicrobial technology of leading antimicrobial provider BioCote® into thermoplastic resin carriers. Defend Rx masterbatches are intended to be dry blended at a 4wt.% let down rate with various thermoplastics to impart antimicrobial performance in finished products. The appropriate Defend Rx masterbatch should be selected based on best pairing the compatibility of the masterbatch carrier with the bulk resin it is being let down into.
Defend Rx masterbatches combat a broad spectrum of microbes to offer hygienic protection to products used in healthcare environments and typical consumer applications. The silver ion technology acts on bacteria by a) changing protein structure which interferes with essential functions such as energy generation, b) damaging cell membranes leading to dehydration and shrinking of the bacteria, c) catalyzing oxidation reactions which damage the internal systems of bacteria, and d) interfering with DNA which prevents bacteria replication. These destruction mechanisms work to significantly reduce living bacteria count on treated surfaces, minimize cross contamination or spread of microbial colonies, minimize material staining and unpleasant odors due to bacterial presence, and increase product lifetimes.

Defend Rx Effectiveness at 4wt.% Let Down Rate
Material Description Test Standard Test Bacterium % Reduction
Pellethane 2363-90A, 4wt.% Defend Rx ISO 22196 S. aureus ATCC 6538P / E.Coli ATCC 8739

99.96 / 99.98
Pebax 7233 SA01 MED, 4wt.% Defend Rx ISO 22196 S. aureus ATCC 6538P / E.Coli ATCC 8739 99.90 / 99.01
Pebax 7233 SA01 MED, 30% BaSO4, 4wt.% Defend Rx ISO 22196 S. aureus ATCC 6538P / E.Coli ATCC 8739 99.96 / 99.99
Lustran 348, 4wt.% Defend Rx ISO 22196 S. aureus ATCC 6538P / E.Coli ATCC 8739 99.89 / 99.99
Makrolon 2458, 4wt.% Defend Rx ISO 22196 S. aureus ATCC 6538P / E.Coli ATCC 8739 99.99 / 99.99
Dow 8907 Health+, 4wt.% Defend Rx ISO 22196 S. aureus ATCC 6538P / E.Coli ATCC 8739 99.70 / 99.99

Product Offerings:
Defend Rx U1000 – Universal Antimicrobial Masterbatch, 4wt.% LDR*
Defend Rx PA2000 – PEBA Antimicrobial Masterbatch, 4wt.% LDR
Defend Rx PU3000 – Thermoplastic Polyurethane Antimicrobial Masterbatch, 4wt.% LDR
Defend Rx Custom – Thermoplastic carrier of choice

*Universal carrier compatible for use in the following: polyolefins, styrenics, polyesters, polycarbonate, polyamides, PEBA, acrylics, thermoplastic polyurethanes, fPVC, and thermoplastic elastomers

Advantages of Defend Rx:
• Excellent thermal and oxidative stability which reduces the risk of material discoloration and improves aesthetics
• Relatively low loading of BioCote antimicrobial needed for high performance
• Relatively low material cost and easy to process compared to other medical antimicrobial technologies
• Consistently high efficacy rates across a variety of microbes in many different thermoplastics
• Longevity of antimicrobial performance for the expected lifetime of the product
• Devices containing Defend Rx technology can continue to use the typical sterilization methods that are recommended for the bulk polymer type and the application


Typical Medical Device Applications:

  • Scopes
  • PICC lines
  • Reusable devices
  • Orthopedic implants
  • Dialysis
  • Wearables
  • Filters/Purification Systems
  • Wound Care
  • Connectors/Adapters
  • Housings
Typical Consumer Good Applications:

  • Food Packaging
  • Fitness / Activity Trackers
  • Sportswear
  • Armbands
  • Headphones
  • Earbuds
  • Eyewear
  • Handheld Devices
  • Electronic / Mobile Phone Cases

Defend Rx masterbatches are available in quantities as low as 1 lb., making them an affordable, high performance solution for protecting your devices.

Disclaimer: BioCote® technology does not protect users or others against disease causing bacteria, germs, viruses or other harmful organisms. This technology is not a substitute for good hygiene and/or cleaning practises.